Systemic Toxicity of Local Anesthetics
نویسندگان
چکیده
منابع مشابه
Local Anesthetics Systemic Toxicity.
Lidocaine Hydrochloride is an amide ester, which is widely used local anesthetic agent that is well tolerated but what is less known is the occurrence of systemic toxicity which manifests in the central nervous and cardiovascular systems. We report here 3 cases of Lidocaine associated Seizures.
متن کاملToxicity of local anesthetics
Systemic neurotoxicity due to excessive cerebral local anesthetic blood levels is one of the most severe and most frequent adverse outcome of local anesthetic use. Toxic levels are most often produced by unintentional intravenous or intraarterial injection(1,2). Toxicity can also result from the rapid absorption of drug following perineural injection. Peak blood levels are usually obtained acco...
متن کاملCardiovascular Toxicity of Local Anesthetics
In general, much greater doses of local anesthetics are required to produce cardiovascular (CV) toxicity than CNS toxicity. Similar to CNS toxicity, potency for CV toxicity reflects the anesthetic potency of the agent. Recent attention has focused on the apparently exceptional cardiotoxicity of the more potent, more lipid-soluble agents (bupivacaine, levo-bupivacaine, etidocaine, ropivacaine). ...
متن کاملFetal toxicity of local anesthetics
This article reviews mechanisms by which local anesthetics may compromise the fetus during conduction analgesia in obstetrics. In addition to presenting pertinent information about perinatal pharmacology of local anesthetics, the author discusses comparative effects of 2-chloroprocaine and amide-linked compounds. Recommendations are made for prevention of maternal hypotension and local anesthet...
متن کاملLocal Anesthetic Systemic Toxicity.
Local anesthetics are commonly used in the perioperative environment to facilitate surgical procedures or to provide postoperative pain management for patients. The use of local anesthetics, however, introduces the risk of complications resulting from local anesthetic systemic toxicity and the risks of increased morbidity and mortality for the surgical patient. Systemic toxicity from the inject...
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ژورنال
عنوان ژورنال: THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA
سال: 2008
ISSN: 0285-4945,1349-9149
DOI: 10.2199/jjsca.28.732